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[7] The concentration of glutathione in the cytoplasm is significantly higher (ranging from 0.5-10 mM) compared to extracellular fluids (2-20 M), reaching levels up to 1000 times greater
Role of NF-B and Akt/GSK3 pathways in the regulation of the expression and activity of CBS The compounds identified in our screening also confirm the importance not only of the Akt/GSK3 pathway but also of NF-B, which is often activated by Akt/GSK3 (Ozes et al., 1999), in the regulation of CBS activity and expression
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Total body mass and fat mass for GSH + CIT was significantly less than placebo at week 8 ( p 0.05)
Collagen types I, III, and IV go up
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