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The literature search was conducted using relevant keywords such as metformin intervention," oxidative stress," antioxidant capacity," and antioxidation." Exclusion criteria for the review included incorrect formulated conclusions, inaccurate study group plurality, unclear criteria for patient inclusion/exclusion, and inconsistent research methodology

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This creates a situation in which patients with certain comorbidities have access, while others with similar weight-related risks do not

For example, this plant compound can mimic and enhance the effects of GLP-1 and has been shown to increase GLP-1 secretion from intestinal cells 14

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