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Most clinical evidence supporting naltrexone in weight management comes from combination trials with bupropion (an antidepressant), where the FDA-approved formulation Contrave demonstrated modest weight loss benefits over 56 weeks
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Epub 2020/02/09
Patients exploring options such as Mounjaro or Zepbound as part of a broader metabolic health conversation with their provider may find it helpful to compare how titration philosophies differ across compounds, since not every option follows the same dosing structure
DOI: 10.1021/acs.jmedchem.1c00565
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