Antioxidants Redox Signal, 18 (12), 14751490
Anlotinib enhances the efficacy of KRAS-G12C inhibitors through c-Myc/ORC2 axis inhibition in non-small cell lung cancer
With aging, muscle stem cell function gradually declines, showing reduced proliferation and fusion, leading to impaired regeneration-one of the key mechanisms underlying sarcopenia.In vitro experiments confirm that 5-amino-1mq significantly enhances the proliferation and fusion of muscle stem cells from aged mice
Glutathione occurs naturally in the body, but levels can decline with age, stress, illness, or exposure to toxins
Deponte M (2013) Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes
Therefore, iron metabolism imbalance, primarily driven by iron overload, is regarded as a critical driver of ferroptosis