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120

Frontiers in Bioscience (Landmark Edition)

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Pechnick, R

In the pancreas , GLP-1 receptor activation stimulates glucose-dependent insulin secretion from beta cells whilst suppressing inappropriate glucagon release from alpha cells

The stabilising D-Ala2 substitution central to the Mod GRF (1-29) / no-DAC GHRH backbone was characterised by Soule and colleagues ( The Journal of Clinical Endocrinology & Metabolism , 1994)