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Past, present and future
Gonalves, J
Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas
Phase 3 trials showed an average A1C drop of around 1.1% over 24 to 30 weeks
The symptoms manifest both in the gastrointestinal tract, skin, cardiovascular, and nervous system
Reported rodent doses for BPC-157 frequently fall in ranges of 10 microg/kg to 10 ng/kg
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