Semaglutide is a glucagon-like peptide 1 (GLP-1) agonist and works by increasing insulin release, reducing the amount of glucagon released, delaying gastric emptying, and reducing appetite
Potential Side Effects Like all medications, semaglutide and tirzepatide can cause side effects, most of which are mild and should decrease as your body adjusts
It's one component of a clinical program that includes dietitian-led nutrition counseling, continuous glucose monitoring when appropriate, and regular clinician check-ins
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They can recommend ways to manage these effects, such as: staying on the lower initiation dose for longer to let your body adjust taking an over-the-counter treatment for digestive problems adjusting your diet, exercise, sleep, or other lifestyle habits If even the lowest maintenance dosage of your GLP-1 medication feels too strong, your prescriber can recommend other, non-GLP-1 alternatives for your condition