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The first clinically measurable weight reductiontypically 24 poundsemerges between weeks two and four for the majority of patients following consistent weekly dosing
Many patients reach 2.4 mg between weeks 16 and 20, though some remain at lower doses longer based on tolerance and results
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Psychological factors such as stress, depression, or inadequate post-operative support can further compromise long-term weight maintenance
The difference is real but not dramaticboth produce substantial weight loss
Understanding potential drug interactions between tirzepatide and disease-modifying therapies (DMTs) for multiple sclerosis is essential for safe prescribing, although direct pharmacokinetic interactions are generally not expected
