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336,337 ECM stiffness further modulates ABC transporter activity, affecting intracellular drug accumulation and compromising the efficacy of chemotherapeutics, targeted agents and ICIs

Low-concentration paclitaxel (36 nM) is reported to interfere with glutaminolysis, a process that is essential for ferroptosis

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It involves removing a portion of the stomach and rerouting the small intestine to reduce the absorption of calories and nutrients