Since the SGLT2-i benefits on HF could not be explained by anti-hyperglycemic action in any of these trials, multiple hypotheses have been raised about the potential mechanisms underlying their cardiovascular favorable effects

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Many people continue with maintenance doses (once weekly or monthly) indefinitely to sustain results
1 So, its unclear whether the results can be generalisable to the broader population
The status of carnitine is evaluated by measuring plasma levels of total carnitine, free carnitine, and acyl-carnitine (17)
Like Ozempic, Wegovy comes in oral and injectable forms