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* The treatment-regimen estimand is the estimated treatment effect, regardless of whether the patient adheres to the treatment, discontinues, or initiates other therapies The efficacy estimand is the estimated treatment effect assuming patients remained on treatment for the entire study duration
Acknowledgements This project was supported by funds from the National Key Research and Development Programme of China to TW under grant number (2023YFD1400300), the National Natural Science Foundation of China to TW under grant number U23A20197 and 31920103014, the Natural Science Foundation of Fujian Province to HC under grant number 2021J01065
Inflammation in Parkinsons Disease: Mechanisms and Therapeutic Implications
Experimental autoimmune encephalitis (EAE) is a well-established animal model that accurately mimics the CNS demyelinating lesions and T-cell responses observed in MS [260]
And, as a malignant disease initiating from the pancreas, it is not clear how pancreatic cancer influences insulin production and synthesis in the pancreas
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