bmi semaglutide Once-weekly 2.4 mg led to significant decreases in body weight and fat mass over 12 months while preserving lean mass and improved muscle function in adults with obesity. Weight and fat Frontiers | Effects of semaglutide

This is an interesting study and an area that should be investigated, given B12 links to neurological health

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While some studies showed higher amounts of stomach contents, aspiration events were rare and occurred at rates similar to patients who were not taking the medications

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Treatment with weekly GLP1s showed sustained weight loss of 15.2% at week 104