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Cancer Res 56 : 40134020 Dunn SE, Ehrlich M, Sharp NJ, Reiss K, Solomon G, Hawkins R, Baserga R, Barrett JC (1998) A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion, and metastasis of breast cancer
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By delivering a powerful biological signal, it forces the body to restart the healing clock, shifting tissue from chronic degeneration to active acute repair
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