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For weight management in the UK, medications like Wegovy are typically prescribed through specialist services for a maximum of 2 years (NICE TA875), while for diabetes management, GLP-1 RAs may be used long-term according to NICE guidance (NG28)

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If adherence and lifestyle factors are optimised, your clinician may consider dose escalation

Some are also exploring other naturally derived ingredients, including specific microbes, plant-based options and dairy derivatives that enhance GLP-1 activity. Companies like Supergut are responding with snack bars and shakes that incorporate resistant starches and beta-glucan, which support gut health in ways similar to the appetite-regulating effects of GLP-1 drugs

Timing depends on your insurance company, pharmacy benefit manager, and whether prior authorization is required

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