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During the first year after treatment began, 27.0% of patients reduced their BMI by less than 5%, 22.4% lost between 5% and less than 10%, 14.1% lost between 10% and less than 15%, and 15.8% reduced BMI by at least 15%
Patient Adherence Injection Burden: Once-weekly dosing improves adherence, but oral formulations (under development) could further enhance compliance
Spacing sessions too far apart allows plasma levels to drop back toward baseline, slowing cumulative progress
Exercise: Finding a Sustainable Routine In one study, people who followed a one-year post-exercise program after stopping liraglutide, another GLP-1 medication that is similar to semaglutide, werent as likely to regain weight
Patient education may need to focus more heavily on older age groups
Participants who switched from three big meals to six small ones reported 41% less nausea than those who stuck with traditional meal patterns
