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This is why lyophilized (dry) storage is far more stable than reconstituted storage: removing water removes the hydrolysis substrate

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In a clinical trial of semaglutide injection for weight loss (Wegovy) in patients with T2DM and a BMI of 27 kg/m2 or more, hypoglycemia (defined as a plasma glucose less than 54 mg/dL) was reported in 6.2% of semaglutide-treated patients versus 2.5% of placebo-treated patients

[Journal of Endocrinology and Metabolism, Year]

(1999) Azathioprine in refractory sprue. American Journal of Gastroenterology

However, a stronger mechanism does not automatically mean it is the right choice for everyone