Current evidence Although B12 supplements are commonly taken to boost energy levels, there is currently no evidence that higher B12 levels increase energy in people with adequate B12 levels
Central nervous system appetite control Both semaglutide and tirzepatide cross the blood-brain barrier and act on appetite centers in the hypothalamus
Simultaneously, it activates GIP receptors, which may influence glucose and lipid metabolism
Those are the types of clues Eli Lillys CEO, David Ricks, says his company will pursue next year, testing whether its GLP-1 drug, tirzepatide (called Mounjaro for diabetes treatment, and Zepbound for weight loss), could help with addiction to alcohol, nicotine, and other things we dont think about [as being] connected to weight. In comments he made in December, Ricks said the drugs might be anti-hedonicsmeaning they counteract our hedonistic pursuit of pleasure, be it from food, alcohol, or drugs
My provider was the most thorough Ive encountered
Standard GLP-1 dosing is supported by randomized clinical trials, while microdosing has not been studied at those same levels