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Our results showed that SUN decreased AMPK with the consequent inhibition of ACC2 phosphorylation and this could increase in ACC2 activity resulting in enhanced production of malonyl-CoA in cardiac tissues from acetyl-CoA
Funding This work was supported by grants from the National Natural Science Foundation of China (NSFC Numbers 81672800, 81603009, 81673020, 81802632, and 82173830), Natural Science Foundation of Shaanxi (2020JQ-445), and the Key Research and Development Program of Shaanxi Province (2021SF-207, 2021SF-223, and 2022ZDLSF05-19)
Tnh an ton v hiu qu glutathione c nghin cu v cng b bi cc tp ch khoa hc uy tn nh Th vin Quc gia Hoa K, Tp ch Direct Science
V., Greenhaff, P
Strengthens the skin barrier with Centella Asiatica complex and Ceramide NP, leaving body skin smooth, supple, and glowing with daily use
Data availability The cryo-EM maps and atomic coordinate models for CDK11-cyclin L-SAP30BP-AMPNP, CDK11-cyclin L-SAP30BP-OTS964 (1 EMDB and 2 PDB entries), CAK-OTS964, and CDK2-cyclin A-OTS964 structures have been deposited in the EMDB with accession codes EMD-53224, EMD-53221, EMD-53205 and EMD-53204 and in the PDB with accession codes 9QKZ, 9QKT, 9QL1, 9QJN and 9QJJ
