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Safety Side Effects & Considerations In the safety department, BPC-157 looks very clean across the preclinical literature
doi: 10.1136/pgmj.22.250.205 PMID: 20997404 Biaggioni I (2021): Adrenoceptor Agonists & Sympathomimetic Drugs (Chapter 9)
Int J Mol Sci (2021) 22(8):3998
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Moreover, as predicted (24), CFTR is easily inactivated by oxidants (30), which would have the same impact as pancreas-selective mutations in CFTR (85), compromising the delivery via ductal cells of bicarbonate into pancreatic juice and, thereby, contributing to lithogenicity (34, 81)
Its also widened the types of groups who now use them
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