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Our study showed a downregulation in Pparg expression after 16 weeks of HCHF intake

And in our modern day world, we don't have to eat plants, we don't have to move anywhere or exercise

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In this context, postbiotics are more plausibly positioned not as primary weight-loss interventions, but as nutritional strategies that may be continued after GLP-1based pharmacotherapy to support metabolic stability, mitigate weight regain, and preserve lean mass during the post-treatment phase ( From a clinical nutrition perspective, postbiotics should not be positioned as weight-loss agents, nor as substitutes for pharmacological GLP-1 receptor agonists

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