As explained in this helpful explainer video, l-carnitine owes its main fat-burning health benefits to two unique functions: Shuttling stored fat into the cell mitochondria (the cell batteries) to be transformed into energy: the mitochondrial shuttle-system allows the transport of fatty acids, as acylcarnitines, from the cytosol into the mitochondrial matrix where these nutrients are oxidized for ATP production AND Encouraging the muscles to use fat for energy during exercise rather than glucose (blood sugar) by priming the cells to run on fat*
It stimulates the pancreas to release insulin, which helps move glucose from the bloodstream into the bodys cells, providing them with energy
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[46] After completing the SURPASS-2 trial (NCT03987919), the company announced in April 2022 that tirzepatide had successfully met its clinical endpoints in obese and overweight participants without diabetes
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Powell-Wiley notes, though, that no single drug even a powerful one can fix the many factors that lead to the development of obesity