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Discovery and development of exenatide: The first antidiabetic agent to leverage the multiple benefits of the incretin hormone, GLP-1
High GPX4 expression is consistently correlated to poor prognosis in patients suffering AML
For example, 500 mg/day of Vitamin C supplementation maintains blood levels of reduced glutathione
A benefit claim alone is not enough to establish fit or safety
The primary mechanism involves tyrosinase inhibition, where glutathione binds to copper at the enzymes active sites to reduce melanin synthesis
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