Mast cell activation syndrome, or MCAS, is an immunological condition where the mast cells in the body release excessive amounts of chemical mediators such as histamine, leading to symptoms such as hives, flushing, rashes, swelling, low blood pressure, dizziness, brain fog, breathing difficulties, and even anaphylaxis
Royal Society of Chemistry
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However, there remained no consensus on effective treatments for chronic rejection, and several therapies targeting the humoral immune system, such as anti-CD20 monoclonal antibodies, have yet to show long-term efficacy (5)
MI and its consequent tissue damage leading to heart failure are mainly responsible for the fatality in patients with T2DM
"Before we had no way of predicting who would benefit from therapies