We actually prefer SQ because its painless and has an established track record of effective B12 delivery, whereas IM can be painful and tends to put people off self-injecting
Of course, people with a proper vitamin B12 deficiency will see more of a benefit, like improvement with less fatigue, nausea, and irritability
If you reconstitute a 30 mg vial with sterile water and plan to draw doses over several weeks, you are creating a contamination risk that increases with every injection
That is not a safe assumption
Exercise particular caution with: Blood pressure medications (nitric oxide effects may alter blood pressure) Immunosuppressive drugs (healing modulation could interact) Growth hormone or related medications (receptor interactions possible) Frequently Asked Questions Glossary of Terms References Sikiric P, et al
Presented for research literature review only Takeishi R et al