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True plateaus, where no weight or measurement changes occur for eight or more consecutive weeks despite consistent adherence, are relatively uncommon during the first six months at 10mg

These findings suggest that retatrutide may offer broader cardiometabolic benefit beyond blood pressure reduction alone

GLP-1 receptor agonists work by enhancing insulin secretion, suppressing glucagon release, slowing gastric emptying, and reducing appetite through action on brain appetite centres

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But some clinicians say that prescribing these drugs is about balancing risk and benefit, not about a person's body size

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