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In the GLP-1 RA group, 33 participants were subsequently newly diagnosed with heart failure, compared with 15 in the SGLT2i group (RR 0.44 [95% CI 0.23, 0.83] p =0.0092)

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Although the direction of association was consistent and statistical heterogeneity was low, serious concerns about indirectness arose because NAION diagnoses were based on administrative coding without ophthalmologic confirmation, and key risk modifiers (optic disc anatomy, rate of glycemic reduction) were not accounted for

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Increased nitric oxide activity has also been demonstrated in resistance trained persons with reactive hyperaemia testing, an assessment used in clinical settings that, to some degree, simulates the physical stresses encountered during very intense exercise such as resistance training [7]

This is usually a result of not eating enough protein, which is why its so important to be mindful of your diet and nutrition while on Semaglutide