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It remains mainly at the animal experimental stage, lacking clinical trial data in humans
In terms of immunology, hormones play a pivotal role by actively controlling the synthesis of antimicrobial peptides (such as -defensins) and cytokines that promote inflammation
Selenocysteine utilization by GPX4 confers exquisite resistance to irreversible overoxidation as cells expressing a cysteine variant are highly sensitive to peroxide-induced ferroptosis [35]
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In adipose tissue, elevated NNMT activity is strongly correlated with obesity, insulin resistance, and cellular aging
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