Zepbound (Injectable) Zepbound (tirzepatide) injectable, a FDA-approved dual GIP and GLP-1 receptor agonist, taken once a week using single use vials and insulin syringes
Not all GLP-1 medications are the same As of April 2026, the most popular GLP-1 medications approved by the Food and Drug Administration include semaglutide, sold under the brand names Wegovy, Ozempic and Rybelsus
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In addition to being highly effective for weight loss, semaglutide and tirzepatide are considered very safe
Based on these data, the FDA approved tesamorelin (marketed as EGRIFTA) for the reduction of excess abdominal fat in HIVassociated lipodystrophy, not as a general weightloss drug for the wider population. Tesamorelin Risks and Considerations Like all hormonemodulating therapies, tesamorelin carries potential risks, including fluid retention, joint pain, injectionsite reactions, and effects on glucose metabolism in susceptible patients