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Glutathione doesn't work in a vacuum

2025;6:1002336 DOI: Received: May 12, 2025 Accepted: August 28, 2025 Published: September 22, 2025 Academic Editor: Nicola Normanno, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) Dino Amadori, Italy The article belongs to the special issue Use of Different Radiation Treatment Modalities in Cancer Therapy: The Role of Inflammation and Immune Response Aim: During radiation treatment, reactive oxygen species (ROS) and nitrogen species (RNS) are produced and, by extension, DNA adducts known as 8-hydroxy-2-deoxyguanosine (8-OHdG) and 8-nitroguanine (8-NG), respectively

In addition, OAT induces proline dehydrogenase (PRODH), leading to mitochondrial ROS production, which further amplifies TGF-1 signaling and tissue fibrosis [71]

The best food sources of folate are dark leafy greens (like spinach and kale), legumes (such as lentils and chickpeas), liver, asparagus, Brussels sprouts, and fortified grains, so be sure to be getting these in your diet frequently