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Resveratrol showed antioxidant activity and anti-A formation features both in vivo , in Tg2576 mice, and in vitro through different molecular mechanisms, including inhibition of -amyloid-induced neuronal apoptosis via regulation of the silent information regulator 1 (SIRT1)-Rho-associated kinase 1 (ROCK1) signaling pathway in PC12 cells and by promoting non-amyloidogenic processing of APP, and thus mitigating A neuropathology in AD (Wang et al., 2006
Glutathione synthetase Glutathione synthetase ( GSS ) (EC 6.3.2.3) is the second enzyme in the glutathione (GSH) biosynthesis pathway
G.van GemertW
E., Sudderth, J., Yue, Y., Zia, A., Glass, D., Deberardinis, R
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433: acute inhalation toxicity: fixed concentration procedure
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