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doi:10.1038/clpt.2010.57

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A B12 shot is an intramuscular injection of vitamin B12 , a crucial nutrient that helps with: Red blood cell production Nervous system function DNA synthesis Metabolism of carbohydrates, fats, and proteins Vitamin B12 is found in animal-based foods, so deficiencies are especially common in vegetarians, vegans, and individuals with absorption issues

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This can be due to having low levels of intrinsic factor in the digestive system, having a digestive condition, or following a plant-based diet