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Whilst gastrointestinal side effects are well-recognised, some patients report itching or skin reactions during treatment

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Adems de la inspeccin visual, est atento a seales clnicas de medicamento ineficaz : Si nota un control glucmico deteriorado sin explicacin (niveles de glucosa en sangre consistentemente elevados), aumento del apetito o prdida del efecto teraputico esperado, esto puede indicar que el medicamento ha perdido potencia debido al almacenamiento inadecuado

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Some animal and early-phase studies noted elevated inflammatory cytokines (IL-6, TNF-) at higher doses, though clinical relevance in humans at therapeutic doses remains unclear