When NNMT is overactive, it consumes S-adenosylmethionine (SAM) and reduces levels of nicotinamide adenine dinucleotide (NAD+), a critical coenzyme involved in cellular energy production
Some of the risks can be serious, such as fluid buildup in the lungs or a blood clot
However, address all other potential causes before switching, as the same factors that cause weight gain on tirzepatide may also affect semaglutide results
Find out in the B-12 section of our B Vitamin Supplements Review
[8] Each individual B vitamin is water-soluble and generally very safe at physiologic doses, but the combination product should only be used when clearly needed
Possible side effects and interactions are usually product-specific, so reading the label and sharing all medicines and supplements with a doctor is important