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However, despite the rather modest weight loss with the drug in this trial, these patients with preserved ejection fraction heart failure demonstrated clinically significant improvements in quality of life, measures of functional capacity, reductions in important biomarkers including NT proBNP and CRP, and numerically less likelihood of heart failure decompensation. In the published paper, the researchers hypothesize that the weight-loss-independent benefits of semaglutide in HFpEF may include direct effects on decongestion

Giustarini D et al

As your dosage increases, so does your monthly cost

The complete contraindication list sits in the FDA label

Many medications, especially those that are biologically derived or contain sensitive compounds, require refrigeration to maintain their efficacy and safety

At first, a GLP-1 medication often offers notable weight reduction