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Autoimmune regulatory (AIRE) gene is primarily expressed by medullary cells in the thymus, which educate T cells to determine antigens that are self versus non-self (Meloni et al., 2012)
Novo Nordisk estimated the figure at 1.5 billion doses over six months
The researchers also noted that 23.5% (95% CI, 22.3-24.8) of people meeting FDA indications for tirzepatide reported using medications that may slow gastrointestinal motility, which could increase gastrointestinal adverse effects when combined with any GLP-1 receptor agonist
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