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Weight management When used alongside GLP-1 therapies, peptides can support appetite regulation and metabolic efficiency
Semaglutide, a long-acting GLP-1 agonist, exhibited a sustained weight decrease of approximately 15% of body weight in clinical studies, whereas tirzepatide, a combination GIP/GLP-1 agonist, attained a weight loss of up to 22.5% in the SURMOUNT trials [36,37]
Triple-Hormone-Receptor Agonist Retatrutide for Obesity, Phase 2 trial
Pharmacol Rev 77:100002
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