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In the APOLLO-B trial (NCT03997383), which enrolled 360 patients with ATTR-CM, compared with placebo, patisiran treatment improved the 6-minute walk distance by 14.7 meters
Some studies have also found that L-carnitine may help reduce symptoms of certain medical conditions such as peripheral artery disease, heart failure, and chronic fatigue syndrome
Other Medications: Metformin users had marginally decreased risk, semaglutide users had unchanged risk, and dulaglutide and liraglutide users had an initially decreased risk which then increased
this association does not imply causation
Atherosclerosis involves more than just cholesterol
For maximum microbiome impact, consider a two-phase approach
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