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In some experiments with MDLCs, the following inhibitors (Sigma) were included: NH 4 Cl (10 mM), bafilomycin A1 (10 nM), dynasore (100 M), methyl beta cyclodextrin (10 mM)
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GIPR fx/fx mice were as described in ref
It was found that both AOD9604 and hGH resulted in fat loss in association with increased fat oxidation as well as increased levels of glycerol (relating to lipolysis), However, an added benefit of AOD9604 was that it did not lead to hyperglycemia in the mice or reduced insulin sensitivity
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