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Glossary Off-label prescribing: Using an approved medicine for a purpose, dose, or population not specifically listed on its official approval CDSCO: Central Drugs Standard Control Organisation Indias national pharmaceutical regulator Grey market: Unauthorized sale of a genuine or counterfeit drug outside licensed, regulated channels Sarcopenia: Loss of muscle mass and strength, a key risk during rapid weight loss BMI: Body Mass Index, a simple weight-to-height ratio used to classify body weight categories External References Han SH, Safeek R, Ockerman K, et al
GLP-1R binds to ligands to internalize GLP-1R, and can independently reduce TG accumulation in hepatocytes by activating key signaling molecules downstream of insulin receptor substrate 2 (IRS2)
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They are used to treat type 2 diabetes mellitus
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Knocking down ACTL6A expression with shACTL6A significantly reduced tumor growth, and NAC treatment (intraperitoneal (i.p.) injection, 200 mg/kg/day) significantly reversed this effect (Fig
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