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others prefer a light meal Anti-nausea options: ondansetron (Zofran) 4 mg 30 minutes before, or ginger supplements Gradual dose increases community protocols describe adding 50-100 mcg every 2-3 days per the titration protocol Facial Flushing Prevalence: 60-70% of users Onset: 15-60 minutes Duration: 1-3 hours Caused by MC1R-mediated vasodilation

Therefore, the anti-inflammatory effect of NSAIDs is mainly applied to peripheral tissues and for short-term inflammation with the limited CNS penetration

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Do not combine it with another GLP-1 medication unless specifically instructed by the prescriber

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