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In this system, Atg4, Atg7, and Atg3 mediate the conjugation of soluble LC3 (microtubule-associated protein 1 light chain 3) to phosphatidylethanolamine (PE), producing LC3-II

We therefore employed two different assays to test whether Prx1 in the mitochondrial matrix can be hyperoxidized at the concentrations of H 2 O 2 used in our acute stress assays

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GSH/APE1 cascade-activated nanoplatform for imaging therapy resistance dynamics and enzyme-mediated adaptive ferroptosis