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An OA mouse model was successfully established by injecting monosodium iodoacetate (MIA) in mouse knee joints 25 , specifically, involving anesthetic administration with 1.25% tribromoethanol (Bimake, M2920) at a dose of 0.2 mL/10 g body weight, followed by intra-articular injection of 10 L MIA (50 mg/ml, Sigma-Aldrich, 57858-25G-F) into the right knee joint using a 30-gauge needle
In the United States, the definition of Barretts esophagus as per the American Gastroenterological Association (AGA) is the condition in which any extent of metaplastic columnar epithelium that predisposes to cancer development replaces the stratified squamous epithelium that normally lines the distal esophagus
Piccoli GF, Mesquita LA, Stein C, Aziz M, Zoldan M, Degobi NAH, et al
In a research note Bernstein analyst Timothy Anderson wrote that the TECOS news removes "a psychological overhang" from the drug and leaves Januvia as "the best-positioned DPP4 in the category," which may allow it to "pick up at least some market share from its direct competitors." At this point, however, some caution may be warranted
10.1111/j.1600-065X.2012.01146.x 136 TienS.ZhouH.ZhouQ.LiuH.WuB.GuoY
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