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Ileal CD is associated with a decreased production of Paneth alpha-defensins in response to sensing of microbes by pattern-recognition of commensal bacteria and pathogens, whereas colonic CD is associated with a reduced expression of HBD1 and a reduced induction of HBD2 and HBD3 also resulting in a reduced mucosal defense [38]
10.1001/archopht.119.10.1417 Jiang H, Yin Y, Wu C-R, Liu Y, Guo F, Li M, Ma L: Dietary vitamin and carotenoid intake and risk of age-related cataract
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