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Summary: Wegovy (semaglutide 2.4 mg) is a GLP-1 receptor agonist that can support weight management in perimenopausal women who meet eligibility criteria, though it is not specifically licensed for perimenopausal symptoms
When activated, Nrf2 disassociates from its repressor protein KEAP1 that reacts with oxidative radicals, translocates to the nucleus, binds to antioxidant response element and induces the transcription of defensive genes
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Abstract Background: With the continuously increasing incidence of type 2 diabetes, glucagon-like peptide-1 (GLP-1) receptor agonists, known for their dual benefits of effectively controlling blood glucose levels while also reducing weight and lowering cardiovascular disease risks, have been widely employed in the treatment of this condition
