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Glutathione gets its nickname, "the master antioxidant," from its ability to hunt down and destroy free radicals, which can impact cellular function
The DDC encoded enzyme is also responsible for the conversion of 5-hydroxytryptophan to serotonin (see below) and in the biosynthesis of several of the trace amine neurotransmitters
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Typical daily range: 5001000 mcg once daily, raised gradually over an 812 week course
Medsafe, June 2025" (PDF)
A May 2025 study in Molecular Therapy from the INc-UAB showed that gene therapy increasing secreted klotho (s-KL) in mice extended lifespan by 15-20% while improving muscle, bone, and cognitive health at 24 months of age (equivalent to ~70 human years)
However, the dose only matters if the nutrient actually makes it into your cells
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