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Without resistance training, creatine provides some cellular-level benefits (cell volumization, hydration), but the majority of its muscle-preserving effects depend on being combined with exercise that challenges your muscles

J Biosci Bioeng 135:2533 Hseu Y-C, Gowrisankar YV, Chen X-Z, Yang Y-C, Yang H-L (2020) The antiaging activity of ergothioneine in UVA-irradiated human dermal fibroblasts via the inhibition of the AP-1 pathway and the activation of Nrf2-mediated antioxidant genes

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In some people, choline deficiency causes muscle damage

It also helps with discoloration and dark patches