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Recent data indicate that UC affects approximately 5 million individuals worldwide as of 2023, with a steadily rising incidence rate (Le Berre et al., 2023)

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This level of flexibility makes it easier to maintain a consistent supply without accumulating unnecessary bottles or worrying about frequent reorders

The drug was voluntarily withdrawn from the US market in 2008 for commercial, not safety, reasons

The 1993 paper framed the work in terms of a stomach-stress-organoprotection hypothesis and reported observations across rat preparations of gastric mucosal injury under various stressors

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