Klinic prescribes four FDA-approved options: Zepbound (tirzepatide injection, once weekly), Wegovy (semaglutide injection, once weekly), Oral Wegovy (semaglutide tablet, once daily), and Foundayo (orforglipron tablet, once daily)
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Delayed stomach emptying followed by accelerated colon transit is a problematic mismatch, which can directly lead to diarrhea
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However, the trial's low event rate and reliance on serum creatinine to assess eGFR, which may be influenced by muscle mass changes, limit the robustness of its conclusions