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Regarding liver tissue fibrosis, Tesamorelin seemed to decelerate its progression, with 10.5% of the Tesamorelin group exhibiting fibrosis progression compared to 37.5% in the placebo group

A few small trials and case reports used oral or parenteral GHK-Cu analogs

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GHK-Cu and Extracellular Matrix Research Research confirms that GHK stimulates synthesis of collagen, dermatan sulfate, chondroitin sulfate, and the small proteoglycan decorin, while also modulating metalloproteinase activity and their inhibitors making it a key compound in extracellular matrix research

As a result, B12 injections give new life to PA patients who would otherwise decline day after day until the disease killed them