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Research shows that glutathione levels in the brain decline with age and are significantly reduced in neurodegenerative conditions like Parkinsons and Alzheimers 9
However, in the posterior cortex, CAT activity was reduced in the VPA+LipRSV group compared to the VPA group, indicating that LipRSV treatment may have negatively modulated the enzymes expression or activity, either by attenuating oxidative stress and thus reducing enzymatic defense needs, or through a possible pro-oxidant effect dependent on the region and experimental conditions
Additionally, BPC 157 naturally occurs in the body, which means that it is well tolerated
However, studies have shown that antioxidant approaches, including anti-neuroinflammatory and neuroprotective agents, may have therapeutic efficacy in the treatment of PD ( The interplay between mitochondrial function and GSH is especially critical in PD
Duffy SL, Lagopoulos J, Hickie IB, Diamond K, Graeber MB, Lewis SJG, et al